BETA 1, 3-D GLUCAN - Balances Macrophage Function Dramatically to Increase Nonspecific Host Resistance

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Beta-1,3 Glucan is a powerful IMMUNE SYSTEM supplement produced from the cell walls of baker's yeast. The amazing immune-activating qualities and protective effects of this substance is supported by many scientific studies. Composition of this product is verified by the University of Georgia, CCRC. The study was supported in part by the Department of Energy-funded (DE-FG09-93ER-20097).

IMMUNE MODULATOR
It has been repeatedly shown in a multitude of studies concerning the activity of beta glucan as an immune stimulator - or perhaps more descriptively, a "biological defense modifier", for the immune system. The aging process has been defined as "the sum total of life's physical embarrassment due to adverse conditions." Beta-1,3-glucan may well be the first true anti-aging nutritional supplement. It is a defense against negative events such as infection, tumors and radiation damage, and adjunctive to the positive effects of antioxidants, lipid balance enhancers, antibiotics and other therapeutics. The result can be improved general health which means greater enjoyment of life, fewer infirmities, less time and money required for medical needs and potentially dramatic savings in health-related expenditures over time.

ANTIOXIDANT EFFECTS
Free radical scavenging assays were repeated in different models which confirmed the antioxidant effect. In light of what is known about the potential of free radicals to accelerate aging, cause cancer and other diseases, this particular effect of Beta-1,3-glucan is especially important.

AN EFFECTIVE ORAL IMMUNOSTIMULANT
Recent independent experiments completed at Baylor College of Medicine in the laboratory of Professor Phil Wyde, Ph.D., also indicate the oral effectiveness of Beta-1,3-glucan in stimulating non-specific immunity. Peritoneal macrophages doubled their phagocyte activity in mice fed with Beta-1,3-glucan. This systemic effect of oral application is comparable to that achieved by injection, which makes this material a unique and very valuable oral immunostimulant.

FIGHTS CANDIDA
Beta-1,3-glucan also has an antifungal effect, shown in experiments with Candida albicans. Such a broad anti-infective spectrum of Beta-1,3-glucan can be explained only by the fact that the immunostimulation produced by this unique material is non-specific.

"Glucan (Beta-1,3) has been shown to enhance macrophage function dramatically, and to increase nonspecific host resistance to a variety of bacterial, viral, fungal, and parasitic infections." M.L. Patchen, Ph.D., Dept. of Experimental Hematology and Radiation Sciences, Armed Forces Radiobiology Research Institute

"Beta-1,3-glucan, is a potent macrophage stimulant and is beneficial in the therapy of experimental bacterial, viral, and fungal diseases." William Browder, M.D., Dept. of Surgery and Physiology, Tulane University School of Medicine

"These studies show, unequivocally, that glucan (Beta-1,3) has an action not only on macrophages, as was originally thought, but also on B lymphocytes and on suppressor T cells." P. Mansell, M.D., McGill University Cancer Research Unit, Victoria Hospital, Montreal, Canada

"A cascade of interactions and reactions initiated by macrophage regulatory factors can be envisioned to occur and to eventuate in conversion of the glucan treated host to an arsenal of defense." Joyce K. Czop, Ph.D., Dept. of Rheumatology and Immunology, Harvard Medical School

"Beta-1,3-glucan is at least 100 times more active than mannan." Joyce K. Czop, Ph.D., Dept. of Rheumatology and Immunology, Harvard Medical School

*Most of this material attributed to: A.J. Lanigan
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This product was analyzed and found to contain Beta-1,3-D-glucan with a total content of 94.3% linked guclose carbohydrates in the sample. The University of Georgia, CCRC, located in Athens, Georgia performed the analysis. The study was supported by the Department of Energy-funded (DE-FG09-93ER-20097).
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